What is the KOOS-12?
KOOS-12 items were selected based on their content along with information from patients, clinicians, and international researchers about item importance and translatability . Item response theory (IRT) models and real-data computerized adaptive test (CAT) simulations also were used to identify items that were best for patients at higher and lower levels of pain and function . Data used for item selection came from a U.S. cohort of nearly 1400 patients with knee osteoarthritis (OA) before and after they underwent a total knee replacement (TKR). Reliability, validity and responsiveness of KOOS-12 scales were evaluated in a separate cohort of nearly 1400 U.S. TKR patients who had knee osteoarthritis .
Each item is scored from 0 to 4, left to right, with 0 representing no knee problems and 4 representing extreme knee problems. The separate KOOS-12 Pain, Function and QOL scale scores are calculated using the method of summated ratings, in which item responses in a scale are simply summed. At least half of the items (i.e. a minimum of 2 items) in the scale must be answered to calculate a scale score, and a person-specific estimate is imputed for any missing item data. KOOS-12 scale scores are transformed so 0 is the worst possible and 100 is the best possible score. This is similar to the method used to score the original KOOS scales, which also are scored using the method of summated ratings and transformed to range from 0 to 100 .
The KOOS-12 Summary knee impact score is calculated as the average of the KOOS-12 Pain, KOOS-12 Function and KOOS-12 QOL scale scores. A Summary impact score is not calculated if any of the three scale scores are missing. The KOOS-12 Summary impact score also ranges from 0 to 100, where 0 is the worst possible and 100 is the best possible score.
An excel-file for calculation of KOOS-12 scores is available at www.koos.nu. This scoring file takes missing items into account, and will not calculate a score if more than 2 items are missing for a scale.
Internal consistency reliability (Cronbach’s alpha) of KOOS-12 scales ranged from 0.75-0.82 (KOOS-12 Pain), 0.78-0.82 (KOOS-12 Function) and 0.80-0.84 (KOOS-12 QOL) before to 6-12 months after TKR in the U.S. knee OA cohort . Internal consistency reliability of the KOOS-12 Summary impact score ranged from 0.90 to 0.93 before to 6-12 months after TKR. Convergent and discriminant validity and responsiveness to TKR of the KOOS-12 Pain, Function and QOL scales were satisfactory and reached similar conclusions as comparable KOOS scales. The KOOS-12 Summary score had high effect sizes and standardized response means post-TKR .
As of March 2019, KOOS-12 measurement properties have been studied in U.S. knee OA patients with end-stage disease who had total knee replacement. It had not been studied yet in patients with early-stage OA or patients with ligamentous injuries.
KOOS-12 does not include the most difficult Sport and Recreation items such as running and jumping. These activities are not performed by some knee OA patients, particularly older patients, and for that reason these items were not included in the 4-item KOOS-12 Function scale. However, these activities can be important for younger, more active patients. Thus, it is recommended that the full KOOS Sport/Recreation scale be administered in addition to the KOOS-12 for patients who aspire to higher-level function, such as those undergoing ACL evaluation. Administering a total of 16 items (KOOS-12 plus 4 additional KOOS Sport/Recreation items) to younger and more active patients allows for calculation of KOOS-12 scale scores and the KOOS-12 Summary impact score along with the KOOS Sport/Recreation scale score. Calculating both the KOOS-12 Function and KOOS Sport/Recreation scales in these patients allows for long-term follow-up of patients who may decline in knee function over time. In these situations, the four items ”squatting”, ”running”, ”jumping” and “kneeling” from the Sport/Rec scale should be added to the questionnaire after the function items and before the QOL items. The “twisting/pivoting” item from the Sport/Rec subscale is already included in KOOS-12.
KOOS-12 translations can be developed in any language for which a KOOS translation is available, by selecting the KOOS-12 items from the full-length KOOS translation. Detailed directions for doing so are forthcoming. No additional linguistic validation is needed to create KOOS-12, if the KOOS translation already exists. If you want to translate the KOOS-12 into a new language for which a KOOS translation is not available, please contact us to be sure no other translation work in your intended language is currently underway. As with the original KOOS, we recommend that you follow the guidelines for cross-cultural validation proposed by Beaton et al. .
KOOS-12 is available free of charge from www.koos.nu. No licensing or permission to use KOOS-12 is required. Please do not change the wording of any part of KOOS-12, or delete any questions or responses. This is for purposes of standardization of content, scoring, and labeling, so users can be assured that the designation KOOS-12 refers to the identical instrument and scoring rules in all cases. This will allow for comparison of scores across multiple studies and other applications.
1. Roos EM, Lohmander LS. Knee injury and Osteoarthritis Outcome Score (KOOS): from joint injury to osteoarthritis. Health Qual Life Outcomes 2003;1:64.